Figure 4. Predicted protein effect of LTBP2 variants on structure–function properties. A–C (first column) show the wild-type in p.C207, p.C1151, and p.C1372. A–C (second column) correspond to the variants of the wild-type described above. The disulfide bond is indicated by the yellow line. The aromatic nucleus is blue. D indicates the predicted overall protein structure of wild-type, p.W417X, and p.W1587X in brown. The transparent part indicates large fragment truncation.