Table 3 of
Tran, Mol Vis 2023; 29:140-152. Table 3 of
Tran, Mol Vis 2023; 29:140-152.
Table 3. Individual cytokines associated with qualitative optical coherence tomography features in eyes with diabetic macular edema at baseline.
| Cytokine | Qualitative OCT features (Mann–Whitney†and Kruskal–Wallis‡) | |||||
|---|---|---|---|---|---|---|
| IRC size‡ H, (p value) | Pattern‡ H, (p value) | HRF‡ H, (p value) | EZ/ELM† W, (p value) | DRIL† W, (p value) | ERM/VMT† W, (p value) | |
| IL-1β | 5.70, (0.06) | 1.03, (0.60) | 2.62, (0.27) | 67.0, (0.81) | 59.0, (0.30) | 41.5, (0.54) |
| IL-1RA | 1.25, (0.53) | 5.59, (0.06) | 3.90, (0.14) | 36.0, (0.06) | 54.5, (0.20) | 63/0, (0.51) |
| IL-4 | 2.64, (0.27) | 0.72, (0.70) | 2.78, (0.25) | 72.0, (1.00) | 97.0, (0.43) | 60.5, (0.62) |
| IL-6 | 3.40, (0.18) | 1.21, (0.55) | 3.53, (0.17) | 75.0, (0.9) | 39.0, (0.04)* | 31/0, (0.22) |
| IL-7 | 0.69, (0.71) | 1.05, (0.59) | 2.88, (0.24) | 44.0, (0.15) | 70.0, (0.62) | 50.5, (0.95) |
| IL-8 | 1.41, (0.50) | 0.65, (0.72) | 1.00, (0.606) | 73.0, (0.98) | 52.0, (0.17) | 39.0, (0.47) |
| IL-9 | 0.50, (0.78) | 1.57, (0.46) | 0.61, (0.74) | 60.0, (0.56) | 66.0, (0.50) | 29.0, (0.18) |
| IL-10 | 1.68, (0.43) | 1.00, (0.61) | 2.19, (0.33) | 60.5, (0.57) | 52.0, (0.17) | 50.0, (0.93) |
| IL-12 | 1.32, (0.52) | 0.98, (0.61) | 1.94, (0.38) | 65.6 (0.76) | 65.6, (0.48) | 46.0, (0.74) |
| IL-13 | 0.40, (0.82) | 2.76, (0.25) | 0.18, (0.91) | 48.0, (0.12) | 44.0, (0.02)* | 37.5, (0.27) |
| IL-15 | 3.06, (0.22) | 3.16, (0.21) | 0.75, (0.69) | 54.0, (0.19) | 74.0, (0.67) | 49.0, (0.83) |
| IL-17 | 2.80, (0.25) | 2.79, (0.25) | 0.02, (0.99) | 64.0, (0.69) | 93.5, (0.53) | 41.5, (0.53) |
| Eotaxin | 1.86, (0.40) | 7.05, (0.029)* | 0.41, (0.82) | 41.0, (0.11) | 82.5, (0.94) | 39.0, (0.45) |
| FGF-β | (6.74, (0.03)* | 0.61, (0.74) | 3.02, (0.22) | 54.0, (0.36) | 114.5, (0.1) | 56.0, (0.83) |
| GM-CSF | 6.99, (0.03)* | 0.40, (0.82) | 2.35, (0.31) | 70.0, (0.94) | 131.0, (0.01)* | 66.0, (0.43) |
| IFN-γ | 7.39, (0.03)* | 0.42, (0.81) | 0.42, (0.81) | 65.0, (0.73) | 69.0, (0.59) | 33.0, (0.25) |
| IP-10 | 0.87, (0.65) | 0.89, (0.64) | 2.05, (0.36) | 48.0, (0.23) | 44.0, (0.08) | 39.0, (0.46) |
| MCP-1 | 3.14, (0.21) | 0.63, (0.73) | 1.78, (0.41) | 70.0, (0.94) | 69.5, (0.61) | 37.0, (0.38) |
| MIP-1α | 2.79, (0.25) | 0.99, (0.61) | 0.11, (0.94) | 60.5, (0.57) | 74.0, (0.77) | 42.5, (0.58) |
| MIP-1β | 0.93 (0.63) | 1.36, (0.51) | 0.54, (0.76) | 66.0, (0.78) | 71.0, (0.67) | 32.0, (0.25) |
| PDGF-β | 3.97, (0.14) | 0.70, (0.71) | 0.08, (0.96) | 46.0, (0.18) | 74.5, (0.79) | 48.0, (0.83) |
| TNF-α | 8.17, (0.02)* | 1.24, (0.54) | 1.91, (0.39) | 53.0, (0.34) | 63.5, (0.42) | 36.5, (0.36) |
| VEGF | 1.76, (0.42) | 1.12, (0.57) | 3.39, (0.18) | 70.0, (0.94) | 70.5, (0.64) | 46.5, (0.76) |
| sVEGFR-1 | 0.46, (0.80) | 1.33, (0.52) | 2.43, (0.30) | 31.5, (0.33) | 25.5, (0.05)* | 23.0, (0.55) |
| sVEGFR-2 | 5.62, (0.06) | 3.51, (0.17) | 0.23, (0.89) | 51.0, (0.68) | 54.5, (0.95) | 43.5, (0.23) |