**Figure 7. **The role of LOX-PP in the cell cycle events in RB. **A:** Flow cytometric analysis and propidium iodide stain showing the percentage of cells in G2, S, and G1. **B:** Representative bar diagram of cell cycle analysis. **C:** Western blot analysis showing the expression of Cyclin D1 in Y79 cells were overexpressed with LOX-PP. **D:** The bar diagram represents the quantification of Cyclin D1 normalized with β-actin. **E:** Western blot for Cyclin D1 in Y79 cells upon treatment with 2.5µg/ml of rLOX-PP. **F:** The bar diagram shows the quantification of Cyclin D1. Values were expressed as mean ± SD, n=3. (Student *t* test statistical analysis was used; ***p<0.001,**p<0.01, and *p<0.05, when compared with EV and vehicle control) (EV, empty
vector; RB, retinoblastoma).