Figure 8. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis of the competing endogenous RNA (ceRNA) networks.
A, B: The top 30 GO terms of biological process (BP), cellular component (CC), and molecular function (MF) categories for upregulated
mRNAs (A) and downregulated mRNAs (B). C, D: The top 20 KEGG pathways of upregulated mRNAs (C) and downregulated mRNAs (D). E: The expression levels of representative genes in mucin-type O-glycan biosynthesis, glycosaminoglycan degradation and PI3K-Akt
signaling pathway (GALNT5, GALNT10, GUSB, GALNS, GNG2) verified by quantitative real-time PCR (qRT-PCR). F: Representative images of immunohistochemical staining to p-PI3K and p-Akt in orbital venous malformation (OVM) and normal
control samples and quantitative analysis.