Table 3 of Lauwen, Mol Vis 2022; 28:536-543.

Table 3. For each of our analyses, we describe the sample sizes, minimally detectable differences with 80% power and the results of the linear regression analyses (ratio of medians, 95% confidence interval and p-value).

AMD status AMD Number of samples per group Minimally detectable difference (in µg/ml) Ratio of medians 95% confidence interval p-value of association
200 35 1.015 0.983-1.048 0.137
  Control 200        
rs61818956 CC 232 37.5 1.009 0.975-1.043 0.22
  CT 138        
rs10494745 GG 332 48.07 1.015 0.942-1.030 0.328
  GA 63        
rs10801582 GG 281 39.71 1.01 0.955-1.025 0.415
  GA 107        
rs794362 AA 365 61.9 0.993 0.941-1.049 0.397
  AG 35        
rs570618 TG 193 40.6 0.995 0.955-1.038 0.027
  GG 120        
rs10922109 CC 180 37.7 0.995 0.962-1.029 0.08
  CA 165        
rs61818924 TA 177 36.8 0.99 0.937-1.047 0.27
  AA 185        

Since one of the genotype groups is small for most of the variants evaluated (Table 1), we calculated power and ratio of medians based on the two largest genotype groups.

Lauwen, Mol Vis 2022; 28:536-543. http://www.molvis.org/molvis/v28/536

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