Table 3 of Sangwan, Mol Vis 2022; 28:526-535.

Table 3. Genotype Frequencies for Interleukin SNPs and SJS/TEN susceptibility.

      Allele 1 versus Allele 2 Dominant Model
11 versus 12+22 Recessive Model
11+12 versus 22
Gene with Genotype Patient (%)
n=100 Control (%)
n=131 p
OR (95% CI) p
OR (95% CI) p
OR (95% CI)
IL-4 promoter (rs2243250)
11 CC
12 CT
22 TT 65 (65)
23 (23)
12 (12) 77 (58.8)
52 (39.7)
2 (1.5) 0.65
- 0.34
- 0.001*
-
IL-4R coding (rs1801275)
11 AA
12 AG
22 GG 70 (70)
25 (25)
5 (5) 66 (50.4)
61 (46.6)
4 (3.1) 0.03*
1.7 (1.1–2.7) 0.003*
2.3 (1.3–4.0) 0.51
-
IL-13 promoter (rs1800925)
11 CC
12 CT
22 TT 69 (69)
29 (29)
2 (2) 87 (66.4)
38 (29.0)
6 (4.6) 0.54
- 0.78
- 0.47
2.3 (0.5–17.2)
IL-13 coding (rs20541)
11 GG
12 GA
22 AA 58 (58)
34 (34)
8 (8) 83 (63.4)
41 (31.3)
7 (5.3) 0.32
- 0.42
- 0.43
-

The Recessive/Dominant model (whichever applicable) were employed for interleukin SNP to check disease susceptibility. *p<0.05.

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