Figure 5. Exchange protein activated by cAMP 1 (Epac1) and a protein kinase A (PKA) agonist reduce NIMA-related kinase 7 (Nek7) and purinergic 2X7 receptor 7 (P2X7) levels in retinal endothelial cells (RECs) grown in normal glucose (NG) and treated with H₂O₂ and Epac1 (A and B) or forskolin (C and D). n = 6. Data are mean ± SEM *p < 0.05 versus NG, # p < 0.05 versus NG + H₂O₂.