Figure 5. The PI3K/AKT pathway is activated by MALAT1-downregulated miR-598-3p. After the Y79 and HXO-RB44 cells were transfected or cotransfected with pcDNA3.1-MALAT1, miR-598-3p mimic, sh-MALAT1, and miR-598–3p inhibitor, the protein expression of the PI3K/AKT pathway-related factors in the Y79 (A) and HXO-RB44 (B) cells was measured with western blotting; **p<0.01.