Figure 4. MALAT1 inhibits miR-598–3p to promote the proliferation of retinoblastoma (RB) cells. After the Y79 and HXO-RB44 cells were
transfected or cotransfected with pcDNA3.1-MALAT1, miR-598-3p mimic, sh-MALAT1, and miR-598-3p inhibitor, the proliferation
ability of the RB cells was determined with (A) cell counting kit-8 (CCK-8) assay and (B) 5-ethynyl-2’-deoxyuridine (EdU) staining (50X). C: Flow cytometry was adopted to assess the apoptotic rate of RB cells.: The expression of apoptosis-related proteins Bax and
Bcl-2 in the Y79 and HXO-RB44 cells was detected with (D) western blotting. *p<0.05, **p<0.01.