Figure 3. Effects of hemichannel inhibitors on ATP release induced by the hypotonic challenge. Time course of ATP release into the media measured from the rat lenses exposed to the hypotonic challenge in the absence or presence of the hemichannel inhibitors carbenoxalone (A, CBX), flufenamic Acid (C, FFA), or probenecid (E, Prob). Mean ATP release into the media from the rat lenses measured after 1 h of exposure to the hypotonic challenge in the absence or presence of CBX (B), FFA (D), or Prob (F). The error bars represent the standard error of the mean, and “()” represents the number of lenses in each experimental group. *p < 0.05.