Figure 3. Transmission electron micrographs of RGCs in the GCL and inner plexiform layer (IPL). Representative ultrastructural images show the presence of double- or multiple-membrane autophagic vesicles (box) containing cell organelles in the cytoplasma of ganglion cell layer (GCL) retinal ganglion cells (RGCs) and dendrites of IPL RGCs of sham-operated (Control) rats or EVC-operated rats treated with vehicle (Operated), TMP (TMP), TMP+Rapamycin (TMP+Rapamycin), or TMP+Ly294002 (TMP+Ly294002). Three eyes were examined in each experimental period.