Figure 3. DEX exposure reduces DNMT enzymatic activity in vitro. Relative enzymatic activity of (A) DNA methyltransferases (DNMTs) and (B) DNMT1 from purified human DNMTs. Upon dexamethasone (DEX) exposure, the activity of the DNMTs was inhibited. (Data are shown as mean ± standard deviation [SD] from three independent experiments.) *p<0.05, **p<0.005 with the Student two-tailed t test.