Figure 4. Docking suggests that inhibitor 9 does not bind to the active site of CYP4V2. In the CYP4V2 homology model, the heme (light blue) is connected to Glu329 by a covalent bond. Inhibitor 9 (green) might complex the heme iron (the red sphere in the center of the heme) but is too far from Arg233 to interact. The lack of interaction between inhibitor 9 and Arg 233 is illustrated by a red cycle.