**Figure 5. **Comparison of the mean concentrations of biomarkers CST4 (**A**), S100A6 (**B**), and MMP9 (**C**) in control (CT; n = 14) and dry eye (DE) groups according to the severity (mild, n = 11; moderate, n = 14; and severe, n
= 7), measured using standard individual ELISA assays and customized multiplexed antibody microarrays. The concentration is
expressed in ng/ml. The insert in the S100A6 plot shows the details of the results obtained using ELISA assays. Error bars
show standard deviation, and * indicates statistical significance relative to the corresponding control group (p value <0.05).