Figure 4 of Dailey, Mol Vis 2021; 27:191-xxx.


Figure 4. Differences in the activation of intracellular signaling between VEGFA165a and VEGFA165b in primary HRMECs begin at the receptor VEGFR2. VEGFA165a was a stronger activator of VEGFR2 compared to VEGFA165b. The median effective dose (ED50) for activation by VEGFA165a was 254 pM compared to 1,192 pM for VEGFA165b. Bars indicate the 95% confidence interval for data fit to the four-parameter log-logistic function. n=4 biologic replicates per dose.