Figure 3 of Gowri, Mol Vis 2020; 26:789-796.

Figure 3. Human mitochondrial genome and detection of primary mutations in LHON samples. A: Schematic representation of the human mtDNA map indicating 37 genes including MT-ND1, MT-ND4 and MT-ND6 as well as the positions of primary mutations. Figure adapted from chimerasthebooks. B: The red arrow demonstrates the internal control of digestion in the MT-ND1 gene product. The yellow arrows indicate the MaeIII restriction, detecting the corresponding mutations marked in blue arrows.