Figure 5. Treatment with tofacitinib differently affects subpopulations of CD8 cells but not of CD4 cells in the eyes and spleen of immunized mice. Cells harvested from inflamed eyes (A) or spleen (B) of immunized mice, treated with tofacitinib or vehicle were analyzed with flow cytometry for expression of CD44 and CD62L. On the left, data of representative mice and on the right, summary of four independent experiments, with four to five mice per group, presented as mean ± standard error of the mean (SEM). Statistical significance was determined using an unpaired t test. *p<0.05.