Figure 5. Relieving of ER stress rescues apoptosis of primary HTM cells. A: Primary human trabecular meshwork (HTM) cells with Myoc-WT or Myoc-N450Y overexpression were subjected to flow cytometry analysis of apoptosis and quantification of apoptosis assay (B). **p<0.05. C: The activity of the PI3K/AKT signaling pathway and expression of apoptosis-related proteins were detected with western blotting. Data were quantified from three independent experiments (n = 3).