Figure 2. IL-6 induces the expression of EMT markers and cytoskeletal reorganization in RPE cells. The expression of the epithelial-mesenchymal transition (EMT) markers collagen type I, fibronectin, N-cadherin, and vimentin was examined with immunofluorescence staining after RPE cells were exposed to 10 and 25 ng/ml of interleukin-6 (IL-6) for 48 h. Scale bars: 40 μm.