Table 3 of
Li, Mol Vis 2020; 26:459-471.
Table 3. Significant enriched terms for GO and KEGG pathways.
Gene Set | Description | N. of Gene | P Value | FDR |
---|---|---|---|---|
GO (biologic process) | ||||
GO:0001568 | blood vessel development | 146 | 0 | 0 |
GO:0001654 | eye development | 92 | 1.78E-15 | 6.04E-14 |
GO:0043010 | camera-type eye development | 80 | 1.06E-13 | 3.01E-12 |
GO:0060041 | retina development in camera-type eye | 45 | 1.05E-10 | 2.13E-09 |
GO:0048592 | eye morphogenesis | 40 | 1.48E-07 | 1.71E-06 |
GO:0048593 | camera-type eye morphogenesis | 28 | 3.19E-05 | 0.000233 |
GO:0003407 | neural retina development | 17 | 8.78E-05 | 0.000565 |
GO:0001754 | eye photoreceptor cell differentiation | 15 | 0.000126 | 0.000774 |
GO:0042462 | eye photoreceptor cell development | 12 | 0.000301 | 0.001645 |
GO:0031290 | retinal ganglion cell axon guidance | 8 | 0.000521 | 0.002611 |
GO:0002088 | lens development in camera-type eye | 17 | 0.001044 | 0.004746 |
GO:0031076 | embryonic camera-type eye development | 11 | 0.003103 | 0.0118 |
GO:0060042 | retina morphogenesis in camera-type eye | 13 | 0.004078 | 0.01461 |
GO:0048596 | embryonic camera-type eye morphogenesis | 8 | 0.008698 | 0.02801 |
GO:0061298 | retina vasculature development in camera-type eye | 6 | 0.001344 | 0.03964 |
KEGG pathway | ||||
mmu04010 | MAPK signaling pathway | 86 | 4.84E-14 | 4.82E-12 |
mmu04151 | PI3K-Akt signaling pathway | 90 | 9.99E-08 | 4.98E-06 |
mmu04210 | Apoptosis | 43 | 1.96E-06 | 3.91E-05 |
mmu04014 | Ras signaling pathway | 62 | 3.22E-06 | 5.67E-05 |
mmu04066 | HIF-1 signaling pathway | 34 | 2.23E-05 | 0.000256 |
mmu04350 | TGF-beta signaling pathway | 28 | 3.89E-05 | 0.000401 |
mmu04150 | mTOR signaling pathway | 42 | 0.000126 | 0.001018 |
mmu04024 | cAMP signaling pathway | 48 | 0.000714 | 0.00368 |
mmu04370 | VEGF signaling pathway | 18 | 0.002992 | 0.01278 |
mmu04310 | Wnt signaling pathway | 35 | 0.003964 | 0.01559 |