Table 2 of
Liu, Mol Vis 2020; 26:378-391. Table 2 of
Liu, Mol Vis 2020; 26:378-391.
Table 2. The potentially disease-causing variants (PDVs) in POAG as compared with control.
| Gene | No. with PDVs in POAG (n=235) | No. with PDVs in control (n=241) | p-value | Odds Ratio Cases:Cont (95% Cl) |
|---|---|---|---|---|
| ABCA1 | 6 (2.6) | 7 (3.0) | 1 | 0.88 (0.24-3.10) |
| ABO | 2 (0.9) | 0 (0) | 0.4989 | - |
| AFAP1 | 3 (1.3) | 0 (0) | 0.1203 | - |
| APOE | 4 (1.7) | 1 (0.4) | 0.211 | 4.14 (0.41-205.29) |
| ASB10 | 3 (1.3) | 2 (0.9) | 1.5439 | 0.58 (0.18-18.63) |
| ATXN2 | 8 (3.4) | 0 (0) | 0.0033 | - |
| CDKN2B | 5 (2.1) | 0 (0) | 0.0287 | - |
| CYP1B1 | 1 (0.4) | 1 (0.4) | 1 | 1.03 (0.01-80.79) |
| EFEMP1 | 5 (2.1) | 1 (0.4) | 0.1184 | 5.20 (0.58-247.49) |
| FNDC3B | 4 (1.7) | 0 (0.4) | 0.0586 | - |
| FOXC1 | 6 (2.6) | 0 (0.4) | 0.014 | - |
| GAS7 | 5 (2.1) | 1 (0.4) | 0.1184 | 5.20 (0.58-247.49) |
| LOXL1 | 6 (2.6) | 1 (0.4) | 0.0648 | - |
| MYOC | 6 (2.6) | 0 (0) | 0.014 | - |
| OPTN | 2 (0.9) | 2 (0.9) | 0.6195 | 1.03 (0.11-121.95) |
| PAK7 | 3 (1.3) | 2 (0.9) | 0.6235 | 0.68 (0.18-18.63) |
| PAX6 | 2 (0.9) | 1 (0.4) | 0.6195 | 2.06 (0.11-121.95) |
| PITX2 | 4 (1.7) | 0 (0.4) | 0.0586 | - |
| TMCO1 | 1 (0.4) | 0 (0) | 0.4937 | - |
| TXNRD2 | 8(3.4) | 1 (0.4) | 0.019 | 7.34 (0.1-376.19) |
| WDR36 | 3 (1.3) | 1 (0.4) | 0.3672 | 3.10 (0.25-163.45) |