Figure 1. Expression of EP1–4 in retina and astrocytes. A: Expression of EP1–4 in adult mouse, rat, and human retinas. B–E: The localization of the EP1–4 receptors in the rat retina. B: Expression of EP1 in the rat retina. C: Expression of EP2 in the rat retina. D: Expression of EP3 in the rat retina. E: Expression of EP4 in the rat retina. Expression of EP1 and EP3 receptors in RGC cytoplasm (shown with an arrow). Expression of EP2 and EP4 receptors in the nucleus of an RGC (shown with an arrow). F, G: Microphotographs of astrocytes immunostained with glial fibrillary acidic protein (GFAP) and vimentin antibodies. H–K: Microphotographs of astrocytes immunostained with EP1–4 antibodies. (40X). The scale bar represents 50 μm. RGC: Retinal ganglion cell.