To access the data, click or select the words “Appendix 1.” Incubation of retinal explants in D-mannitol did not significantly alter key metabolite levels and enzyme activities. A: Glucose levels (p = 0.588). B: Lactate levels (p = 0.220). C: ATP levels (p = 0.051). D: Glutamate levels (p = 0.877). E: Glutamine levels (p = 0.274). F: CK activity (p = 0.436). G: LDH activity (p = 0.871). H: AST activity (p = 0.543). I: GDH activity (p = 0.713). Student’s t-test was used to determine statistical significance. Values represent mean ± standard error of the mean. Abbreviations: C-control, M- D-mannitol.