Figure 6. Activated microglia activity at P19, P24, P32, and P47 in RA and OIR mice. A: Iba1 staining in the retinas of the RA mice. B: The white arrow denotes activated microglia. C: Activated microglia in OIR mice (magnified view from each age in B). D: Quantification of total microglial cells and activated microglial cell densities. Three RA mice and three OIR mice were examined for each developmental age studied. RA = room air; OIR = oxygen-induced ischemic retinopathy; P = postnatal day. Stars denote level of significance: *p< 0.05, **p< 0.01, ***p< 0.001, and ****p< 0.0001. Sampling size: n=3 for each group. Error bars represent SEM.