Figure 4. Deletion of p62 in Cx50D47A/D47A mice does not alter levels of lens fiber connexins. A, B: Top panels, Immunoblots of Cx46 (A) and Cx50 (B) in lens homogenates prepared from 1-month-old Cx50D47A/D47A mice that were wild-type for p62 (p62+/+-Cx50D47A/D47A) or heterozygous (p62+/−-Cx50D47A/D47A) or homozygous (p62−/−-Cx50D47A/D47A) p62 null. The migration positions of the molecular mass markers are indicated on the left. The graphs at the bottom show the
quantification of the density of the Cx46 (A) and Cx50 (B) immunoreactive bands in arbitrary units (a.u.). Data are presented as the mean (bar) + standard error of the mean (n = 6
sets for Cx46; n = 3 sets for Cx50).