Table 1 of
Tian, Mol Vis 2020; 26:1-13. Table 1 of
Tian, Mol Vis 2020; 26:1-13.
Table 1. The results of enrichment analysis for the differentially expressed mRNAs.
| Category | Term | Count | P-value | FDR |
|---|---|---|---|---|
| Biology Process | GO:0006811~ion transport | 78 | 1.69E-11 | 3.01E-08 |
| GO:0007267~cell-cell signaling | 62 | 1.49E-09 | 2.65E-06 | |
| GO:0009611~response to wounding | 55 | 1.30E-08 | 2.31E-05 | |
| GO:0030001~metal ion transport | 49 | 5.78E-08 | 1.03E-04 | |
| GO:0006955~immune response | 63 | 1.17E-07 | 2.08E-04 | |
| GO:0006812~cation transport | 54 | 1.34E-07 | 2.40E-04 | |
| GO:0002526~acute inflammatory response | 19 | 3.03E-07 | 5.39E-04 | |
| GO:0006952~defense response | 57 | 3.18E-07 | 5.67E-04 | |
| GO:0006959~humoral immune response | 17 | 3.43E-07 | 6.11E-04 | |
| GO:0019226~transmission of nerve impulse | 39 | 4.14E-07 | 7.37E-04 | |
| GO:0007268~synaptic transmission | 35 | 5.40E-07 | 9.62E-04 | |
| GO:0006954~inflammatory response | 36 | 1.44E-06 | 2.56E-03 | |
| GO:0006956~complement activation | 12 | 1.63E-06 | 2.90E-03 | |
| Cellular Component | GO:0005576~extracellular region | 166 | 8.85E-13 | 1.22E-09 |
| GO:0005886~plasma membrane | 264 | 2.56E-12 | 3.53E-09 | |
| GO:0044421~extracellular region part | 97 | 4.47E-12 | 6.16E-09 | |
| GO:0044459~plasma membrane part | 173 | 1.84E-11 | 2.54E-08 | |
| GO:0031224~intrinsic to membrane | 348 | 1.92E-11 | 2.65E-08 | |
| GO:0005615~extracellular space | 74 | 1.32E-10 | 1.83E-07 | |
| GO:0016021~integral to membrane | 334 | 2.43E-10 | 3.35E-07 | |
| GO:0031226~intrinsic to plasma membrane | 106 | 2.24E-09 | 3.10E-06 | |
| GO:0005887~integral to plasma membrane | 104 | 2.84E-09 | 3.92E-06 | |
| GO:0034702~ion channel complex | 27 | 6.91E-06 | 0.009529 | |
| Molecular Function | GO:0015267~channel activity | 51 | 1.14E-10 | 1.74E-07 |
| GO:0005216~ion channel activity | 49 | 1.17E-10 | 1.78E-07 | |
| GO:0022803~passive transmembrane transporter activity | 51 | 1.24E-10 | 1.88E-07 | |
| GO:0022838~substrate specific channel activity | 49 | 3.38E-10 | 5.15E-07 | |
| GO:0022836~gated channel activity | 40 | 4.97E-09 | 7.56E-06 | |
| GO:0005261~cation channel activity | 33 | 7.27E-07 | 1.11E-03 | |
| GO:0005509~calcium ion binding | 71 | 7.41E-06 | 1.13E-02 | |
| GO:0046873~metal ion transmembrane transporter activity | 34 | 1.19E-05 | 1.81E-02 | |
| GO:0022834~ligand-gated channel activity | 19 | 1.40E-05 | 2.13E-02 | |
| GO:0015276~ligand-gated ion channel activity | 19 | 1.40E-05 | 2.13E-02 | |
| GO:0030594~neurotransmitter receptor activity | 16 | 1.97E-05 | 2.99E-02 | |
| Pathway | hsa04080:Neuroactive ligand-receptor interaction | 35 | 7.65E-08 | 1.07E-05 |
| hsa04610:Complement and coagulation cascades | 15 | 5.01E-06 | 3.51E-04 | |
| hsa04940:Type I diabetes mellitus | 11 | 2.69E-05 | 1.26E-03 | |
| hsa00982:Drug metabolism | 13 | 3.97E-05 | 1.39E-03 | |
| hsa00140:Steroid hormone biosynthesis | 10 | 3.43E-04 | 9.55E-03 | |
| hsa04060:Cytokine-cytokine receptor interaction | 26 | 1.07E-03 | 2.47E-02 | |
| hsa05330:Allograft rejection | 8 | 1.64E-03 | 3.22E-02 | |
| hsa04020:Calcium signaling pathway | 19 | 2.53E-03 | 3.86E-02 | |
| hsa00980:Metabolism of xenobiotics by cytochrome P450 | 10 | 2.51E-03 | 4.30E-02 |