Table 2 of Oliver, Mol Vis 2019; 25:93-105.

Table 2. Summary of number of dogs, results of quality control filtering steps and correction of population stratification for the five GWAS analyses.

Analysis Phenotype of cases Phenotype of controls No. cases No. controls SNPs with MAF <0.05 SNPs with <0.97 call rate SNPs remaining for analysis λ before correction λ after correction P value
1 PCAG Controls 24 37 71,687 11,749 96,259 1.96 1.04 1.7×10−4
2 PCAG + PLA Controls 81 37 71,633 10,166 97,282 1.34 1.00 7.7×10−5
3 PLA Controls 57 37 73,253 11,935 94,781 1.28 1.01 1.0×10−4
4 PCAG PLA 24 57 72,150 9,858 96,868 2.23 1.01 3.8×10-7*
5 PCAG Controls + PLA 24 94 71,633 10,166 97,282 2.25 0.96 1.4×10-7*

No.=number, λ=lambda (genomic inflation factor), * denotes significant association (Bonferonni)

Oliver, Mol Vis 2019; 25:93-105. http://www.molvis.org/molvis/v25/93

©2019 Molecular Vision http://www.molvis.org/molvis/

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