Figure 2 of Nitta, Mol Vis 2019; 25:859-868.


Figure 2. Effects of crocetin by eye drops on retinal thickness in the murine RVO model. A: Experimental protocol in vivo with eye drops of crocetin. Crocetin was administered immediately, 6 h, and 12 h after laser irradiation by eye drops. The retina was evaluated 24 h after laser irradiation. B: Representative images of hematoxylin and eosin (H&E) staining in control, vehicle-treated, and crocetin-treated groups are shown 1 day after laser irradiation. Scale bar represents 50 µm. C: Graphs show the thickness of the inner nuclear layer (INL). The increase in the thickness of the INL was suppressed with the administration of crocetin. Data are shown as mean ± standard error of the mean (SEM; n=3 or 4). #p<0.05, ##p<0.01 (versus control group; Student t test). *p<0.05, **p<0.01 (versus vehicle group; Student t test). INL, inner nuclear layer; ONL, outer nuclear layer.