Table 1 of Okazaki, Mol Vis 2019; 25:843-850.

Table 1. Allelic associations between 10 SNPs with p<0.05 and lattice degeneration of the retina in the Japanese population.

SNP Position on
Chr.12  
Risk
Allele Risk Allele Frequency  
P Pc OR (95% CI) adjP* adjPc adjOR (95% CI)* Rsq
Score**
Cases
(n = 634) Controls
(n = 1694)
(GRCh37) Alleles
rs12721423 48363024 C>A A 0.478 0.438 0.015 0.19 1.17 (1.03–1.34) 0.1   1.14 (0.97–1.35) 0.739
rs34829929 48364881 C>T T 0.478 0.437 0.012 0.16 1.18 (1.04–1.34) 0.094   1.15 (0.98–1.35) 0.757
rs28594309 48365733 A>G G 0.478 0.437 0.011 0.15 1.18 (1.04–1.34) 0.091   1.15 (0.98–1.35) 0.765
rs3829735 48376599 G>A G 0.94 0.915 0.005 0.065 1.45 (1.12–1.89) 0.062   1.36 (0.98–1.89) Genotyped
rs2023939 48388612 A>G A 0.774 0.744 0.03 0.38 1.18 (1.02–1.38) 0.016 0.21 1.27 (1.04–1.55) 0.969
rs12308909 48393098 G>A G 0.764 0.727 0.01 0.13 1.22 (1.05–1.41) 0.0055 0.072 1.31 (1.08–1.60) 0.955
rs1635533 48393137 G>A G 0.68 0.6305 0.0017 0.023 1.24 (1.09–1.43) 0.0038 0.049 1.29 (1.08–1.55) 0.977
rs1793954 48393320 C>T C 0.68 0.6302 0.0016 0.021 1.25 (1.09–1.43) 0.0036 0.047 1.30 (1.09–1.55) 0.978
rs1635532 48393444 G>A G 0.679 0.642 0.017 0.22 1.18 (1.03–1.36) 0.026 0.34 1.22 (1.02–1.46) 0.993
rs1793953 48393526 C>T C 0.689 0.644 0.004 0.053 1.22 (1.07–1.41) 0.017 0.22 1.24 (1.04–1.47) Genotyped

Chr., chromosome; OR, odds ratio; CI, confidence interval; adjP, p value adjusted for spherical equivalent; adjOR, OR adjusted for spherical equivalent. * The adjP values and adjORs were determined using logistic regression. **Rsq is an estimate of the squared correlation between imputed and true genotypes., minor allele frequency; LP, likely pathogenic; P, pathogenic; VUS, a variant of uncertain significance

Okazaki, Mol Vis 2019; 25:843-850. http://www.molvis.org/molvis/v25/843

©2019 Molecular Vision http://www.molvis.org/molvis/

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