Figure 1 of Okazaki, Mol Vis 2019; 25:843-850.


Figure 1. Allelic association results for the COL2A1 gene region with lattice degeneration of the retina in the Japanese population. The SNP showing the strongest association (rs1793954) is depicted as a purple diamond. The color coding of the other SNPs indicates linkage disequilibrium (LE) with rs1793954: red, r2 ≥0.8; yellow, 0.6 ≤ r2 <0.8; green, 0.4 ≤ r2 <0.6; cyan, 0.2 ≤ r2 <0.4; blue, r2 <0.2; and gray, r2 is unknown. The left y-axis represents the −log10 p values for allelic association with lattice degeneration of the retina, and the right y-axis represents the estimated recombination rate. The horizontal blue and red lines indicate p = 0.05 and Pc = 0.05 (p = 0.00385 [0.05/13 SNPs]), respectively. Gene annotations are shown below the figure. The plot was created using LocusZoom.