Table 4 of
Xu, Mol Vis 2019; 25:834-842. Table 4 of
Xu, Mol Vis 2019; 25:834-842.
Table 4. Frequencies of alleles and genotypes PRKCQ polymorphisms in patients and controls in the second stage and combined results
| SNP | Genotype allele | Second-stage | Meta-analysis | ||||
|---|---|---|---|---|---|---|---|
| Cases (n=259) | Controls (n=542) | P value (OR, 95% CI) | Pc | P value | (OR, 95% CI) | ||
| rs4750316 | GG | 246 (94.98) | 451 (83.21) | Reference | |||
| GC | 12 (4.63) | 88 (16.24) | 3.23e-6 (OR=0.25, 95% CI= 0.13–0.47) | 7.75e-5 | 2.45e-10 | (OR=0.37, 95% CI= 0.28–0.51) | |
| CC | 1 (0.39) | 3 (0.55) | 0.67 (OR=0.61, 95% CI= 0.063–5.91) | NS | 0.47 | (OR=0.61, 95% CI= 0.16–2.30) | |
| G | 504 (97.30) | 990 (91.32) | Reference | ||||
| C | 14 (2.70) | 94 (8.67) | 8.32e-6 (OR=0.29, 95% CI= 0.16–0.52) | 0.0002 | 8.79e-10 | (OR=0.41, 95% CI= 0.31–0.55) | |