Figure 3. PhTX does not change the cone-driven AMPA receptor-mediated EPSCs of DACs. The α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) receptor-mediated light-induced excitatory postsynaptic currents (EPSCs) of dopaminergic amacrine cells (DACs) were recorded in the presence of a cocktail of antagonists (see Figure 1) from retinas of cone-function-only TH::RFP mice. The DAC light-induced EPSCs were unchanged in the presence of 5 µM PhTX. A representative recording is illustrated in (A). Average data (mean ± standard error of the mean (SEM)) are shown in (B; n=3, n.s. p>0.05, paired t test). The data suggest that the AMPA receptors that mediate cone-driven DAC light responses are unlikely Ca²⁺-permeable subtypes.