Figure 5. Deletion of Chop in Cx50^D47A/D47A mice does not alter levels of lens fiber connexins. A, B: Immunoblots of connexin50 (Cx50; A, top) and connexin46 (Cx46; B, top) in lens homogenates prepared from 1-month-old Cx50^D47A/D47A mice that were wild type for Chop (Chop^+/+) or heterozygous (Chop^+/−) or homozygous (Chop^−/−) Chop knockout. The migration positions of the molecular mass markers are indicated on the left. Graphs at the bottom show the quantification of the density of the Cx50 (A) and Cx46 (B) immunoreactive bands. Data are presented as the mean (bar) + standard error of the mean (n = 5 sets for Cx50; n = 3 sets for Cx46).