Figure 1. Deletion of Chop does not affect lens transparency. A: Dark-field photomicrographs of lenses from wild-type Chop (Chop^+/+) and heterozygous (Chop^+/−) and homozygous (Chop^−/−) Chop knockout mice at 1 month of age. Scale bar: 474 µm. B: Graph showing the equatorial diameters determined from dark-field photomicrographs of lenses from wild-type Chop (Chop^+/+) and heterozygous (Chop^+/−) and homozygous (Chop^−/−) Chop knockout mice (n = 4 biological replicates). The data points are presented with different symbols, each indicating a different set (containing all three genotypes) of lenses from littermate mice. Bars represent the mean. The asterisk denotes significant differences from Chop^+/+ (p<0.05).