Figure 4. Top 50 groups of SNPs were highly associated with three metabolites significantly changed in common between patients with
PCG and any other kind of patients (with CCs/ARCs/POAG) according to an enrichment analysis using the MetaboAnalyst web server
with the SNP-associated metabolite set library (4501 SNPs). The details of three SNPs, including
rs7114303,
rs9364602, and
rs2165241, are shown. PCG: primary congenital glaucoma; CCs: congenital cataracts; ARCs: aged-related cataracts; POAG: primary open
angle glaucoma. *All SNPs in this group are shown in Appendix 8.