Figure 2. Exercise provides partial preservation of spatial frequency in induced I307N Rho degeneration mice. The inactive mice that underwent induced retinal degeneration (red bar) exhibited spatial frequency thresholds (as measured with optomotor response [OMR]) that were statistically significantly lower than those of the uninduced mice (black and blue bars) 4 weeks degeneration was induced. The induced mice that were active (green bar), however, exhibited a mean spatial frequency threshold that was statistically indistinguishable from those of the uninduced groups, but was statistically significantly greater than inactive, induced mice. **p<0.01 and *p<0.5 with one-way ANOVA with the Newman-Keuls multiple comparisons test; comparisons as indicated in figure. n=5–7 mice/group. Error bars represent standard error of the mean (SEM).