Appendix 1 of Zyla, Mol Vis 2019; 25:446-461.


Appendix 1. The preventive regimen with DMF modestly preserves visual acuity.

(A) Graph of the average number of days that mice on the preventive regimen registered an OKT reading deficit of 10% (left graph), 20% (center graph), or 30% (right graph) below their respective baseline OKT readings as a function of treatment with DMF (blue bar) or vehicle (red bar). (B) Graph of the average lowest OKT readings for mice on the preventive protocol with DMF or vehicle. (C) Graph of the average number of optic neuritis episodes for mice on preventive treatment with DMF or vehicle. (D) Graph of the average difference between baseline and final OKT readings for mice on preventive treatment with DMF or vehicle. Statistics for all graphs determined by Mann–Whitney U test, ‘ns’ denotes not significant, and asterisk denotes statistically significant (p<0.05). Error bars represent SEM; n=8 mice for each treatment group. To access the data, click or select the words “Appendix 1.”