Figure 7. Treatment of corneal scarification with UMSCs. A 2-mm central keratectomy was created in C57BL/6J mice and left alone for
14 days at which time a scar developed. After 2 weeks, umbilical cord mesenchymal stem/stromal cells (UMSCs) were transplanted
via a fibrin carrier onto the surface of the eye. A: A montage acquired from a volumetric scan using in vivo confocal microscopy (Heidelberg retinal tomograph, HRT II). Three
panels 5 μm apart showing the cornea stroma (anterior to posterior). B: Pixel intensity of the stroma was obtained using Image J software. Data show no statistically significant difference between
the UMSC-treated and control groups. Days represent time after keratectomy with treatment at 14 days.