Figure 1. Recovery of corneal transparency in Col5a1^Δst/Δst mice after UMSC treatment. A,B: Heidelberg retinal tomograph (HRT II) was performed on Col5a1^Δst/Δst mice before (A) and 7 days after umbilical cord mesenchymal stem/stromal cell (UMSC) treatment (B). Three-dimensional renderings from volumetric scans were created using AxioVision 4.7 software. Corneal transparency recovers in collagen V-null corneas 7 days post-UMSC transplantation. C,D: Immunofluorescent staining for anti-collagen V antibodies in UMSC-treated (C) and control (D) eyes after 7 days. Note the Col5a expression in the corneal stroma; images from the peripheral cornea.