Figure 6. An example of a true differentially expressed gene.
A: Expression levels of
Stab2 mRNA (y-axis) across the BXD strains (x-axis) from the Department of Defense (DoD) database (Probe_17243763).
B: Probe verification at UCSC demonstrates that there is no single nucleotide polymorphism (SNP) in the probe coverage area.
C: This gene is also identified as a differentially expressed gene in the RNA sequencing (RNA-seq) data. Viewing the RNA-seq
signal in the Integrative Genomics Viewer (
IGV) browser further confirms that this gene is highly expressed in D2 mice in all the exons, while there is no signal for the
B6 mice.