Figure 6. Decrease in AH outflow facility and an IOP elevation in mice treated with CBX or FFA. A: Outflow facilities were measured in mice at 5 days after injection. Compared to the average value of the outflow facility in vehicle control, decreased outflow facility was observed after carbenoxolone (CBX) or flufenamic acid (FFA) treatment. * p≤0.05. B: Intraocular pressure (IOP) was measured every day after intracameral injection of CBX or FFA. Compared to the IOP in the control mice (n=28), the IOP was increased statistically significantly after treatment with either CBX (n=15) or FFA (n=19).