Table 2 of
Lu, Mol Vis 2019; 25:222-236. Table 2 of
Lu, Mol Vis 2019; 25:222-236.
Table 2. Significant enriched genes pathways.
| Pathway Name | N | FDR p value | Genes in the pathway |
|---|---|---|---|
| TCA Cycle | 7 | 0.0002 | Pdk1 Fh1 Pdk4 Idh2 Pdk2 Sdhd Dld |
| MAPK signaling pathway | 12 | 0.0031 | Dusp6 Dusp10 Stmn1 Ppp5c Dusp4 Mapk6 Akt3 Map4k4 Hspa1a Map3k12 Dusp1 Map3k5 |
| Focal Adhesion | 12 | 0.0037 | Ppp1r12a Vegfc Tnxb Rhob Pak7 Araf Mapk6 Pak4 Flt1 Akt3 Vegfb Itga9 |
| One carbon metabolism and related pathways | 6 | 0.0037 | Gclc Cth Gsr Gss Chka Gnmt |
| Glycolysis and Gluconeogenesis | 6 | 0.0037 | Tpi1 Pfkm Pfkp Slc2a3 Dld Hk1 |
| Amino Acid metabolism | 9 | 0.0041 | Fh1 Bcat1 Cth Gss Sdhd Glud1 Pdk4 Gsr Dld |
| Myometrial Relaxation and Contraction Pathways | 9 | 0.0209 | Rgs10 Ywhaz Rgs5 Camk2g Cald1 Rgs2 Prkd1 Igfbp2 Prkar1a |
| Glutathione and one carbon metabolism | 4 | 0.0214 | Gclc Cth Gsr Gss |
| Electron Transport Chain | 6 | 0.0271 | Slc25a4 Slc25a14 Atp5b Ndufs4 Atp5j Sdhd |
| Mitochondrial Gene Expression | 3 | 0.0319 | Pprc1 Tfam Nrf1 |
| Chemokine signaling pathway | 9 | 0.0319 | Nfkbib Cxcl14 Cxcl16 Prkx Akt3 Adrbk1 Cx3cl1 Nfkbia Csk |
| Calcium Regulation in the Cardiac Cell | 8 | 0.0319 | Atp1b1 Rgs10 Ywhaz Rgs5 Camk2g Rgs2 Prkd1 Prkar1a |
| Glutathione metabolism | 3 | 0.0319 | Gclc Gsr Gss |
| Apoptosis | 6 | 0.0403 | Xiap Nfkbib Bcl2l2 Dffa Nfkbia Cycs |
| EGFR1 Signaling Pathway | 10 | 0.0403 | Pebp1 Ralbp1 Araf Ceacam1 Git1 Prkd1 Dusp1 Csk Tgif1 Prkar1a |
| Insulin Signaling | 8 | 0.0408 | Mapk11 Mapk6 Pfkm Map4k4 Trib3 Gys1 Map3k12 Map3k5 |
| Regulation of Actin Cytoskeleton | 8 | 0.0408 | Ppp1r12a Pak7 Mapk6 Pak4 Limk1 Gsn Git1 Csk |
| Translation Factors | 4 | 0.0408 | Eif2b1 Eef1a2 Eif1a Eef2 |
| Oxidative Stress | 3 | 0.0408 | Gclc Gsr Txn2 |
| Integrin-mediated cell adhesion | 6 | 0.041 | Akt3 Araf Mapk6 Pak4 Csk Itga9 |
| B Cell Receptor Signaling Pathway | 9 | 0.041 | Dusp6 Plekha1 Dusp4 Pdk2 Cd81 Hnrnpk Prkd1 Nfkbia Csk |