Figure 1. Ophthalmic and histological appearance immediately after subretinal injections of PBS. A: Subretinal blebs visualized by surgical microscopy immediately after subretinal injection (arrows, delimitation of retinal detachment extensions). B: Separation between the neuroretina and retinal pigment epithelium in the superior temporal quadrant of the eye (subretinal injection area). No significant damage was evident in the neuroretina or in the retinal pigment epithelium/choroid. Photoreceptor outer segment debris was present in the subretinal space (arrows). Haematoxylin and eosin staining, scale bar: 250 µm.