Figure 1. Pedigrees of Pakistani families with PCG with segregated variants in CYP1B1. Pedigrees of 14 multigenerational families who segregated recessive primary congenital glaucoma (PCG) due to disease-causing variants in CYP1B1. Filled and empty symbols represent affected and unaffected individuals, respectively. A double line connecting two individuals represents consanguineous marriage. Genotypes are written at the bottom of the enrolled individuals. Shown also are eye photographs of representative affected individuals. All the affected individuals have hazy corneas.