Figure 3. Anterior segment images using optic coherence tomography (OCT) in Yap1^+/- and WT mice. A: Fourier-domain optical coherence tomography demonstrates the normal anterior segment of male wild-type (WT) mice at the indicated age: 2 weeks old, 2 months old, and 1 year old. B: The Yap1^+/− mice demonstrate corneal pathology and anterior segment anomalies at all ages. A thin cornea with adherent iris (arrowhead), a collapsed anterior chamber, and aphakia in age-matched male Yap1^+/− mice at 2 weeks old, 2 months old, and 1 year old. A small lens and a deep anterior chamber were identified in the left eye of a 1-year-old male Yap1^+/− mouse. A, anterior chamber; C, cornea; I, iris; L, lens.