Normal retinal morphology was observed in young (2 weeks and 2 months old) WT (A, B and E, F, respectively) and Yap1^+/− (C, D and G, H, respectively) mice. For the Yap1^+/− and WT mice examined 2 weeks after birth, a small vessel extending from the optic nerve head into the vitreous consistent with a hyaloid artery (HA) was observed. At the same time, there were small and regularly distributed vessels free floating in the vitreous chamber, suggesting the presence of a tunica vasculosa lentis (TVL). The TVL and HA are appropriate for this developmental stage. In comparison with the normal retina of 1 year old WT mice (I, J), retinal detachment accompanied with subretinal accumulation of macrophages, hypertrophy of the retinal pigment epithelial cells and light proteinaceous exudate was also observed in a mouse in one year old Yap1^+/− mice with retinoschisis (K, L). Thinned retinas due to loss of outer nuclear and photoreceptor layers were also common findings at this age in Yap1^+/− mice. To access the data, click or select the words “Appendix 4.”