Table 1 of
Papadopoulou, Mol Vis 2018; 24:890-901. Table 1 of
Papadopoulou, Mol Vis 2018; 24:890-901.
Table 1. Protein carbonyl level and concentration change versus age in CAT, PEX, POAG and PXG.
| Sample | Ocular Disease | Experimental values | Tukey's multiple comparisons test1 | Adjusted P-value / samples (n1/n2) | Signifi-cance degree |
|---|---|---|---|---|---|
| A. Rate of protein carbonyl level increase per age versus disease | |||||
| Slope rate values (± SE) | |||||
| from Figure 1A (in nmoles carbonyls ml-1 per 5-year interval) | CAT vs. PEX | <0.0001 (33/31) | **** | ||
| CAT vs. POAG | <0.0001 (33/19) | **** | |||
| AH | CAT | 0.803 ± 0.060 | CAT vs. PXG | <0.0001 (33/17) | **** |
| PEX | 1.770 ± 0.110 | PEX vs. POAG | =0.2021 (31/19) | ns2 | |
| POAG | 2.049 ± 0.127 | PEX vs. PXG | <0.0001 (31/17) | **** | |
| PXG | 2.489 ± 0.096 | POAG vs. PXG | =0.0146 (19/17) | * | |
| from Figure 1B (in nmoles carbonyls mg-1 protein per 5-year interval) | CAT vs. PEX | <0.0001 (20/19) | **** | ||
| CAT vs. POAG | =0.0328 (20/17) | * | |||
| AH | CAT | 4.939 ± 0.310 | CAT vs. PXG | =0.2351 (20/18) | ns |
| PEX | 8.768 ± 0.423 | PEX vs. POAG | =0.0002 (19/17) | *** | |
| POAG | 6.403 ± 0.476 | PEX vs. PXG | <0.0001 (19/18) | **** | |
| PXG | 5.921 ± 0.234 | POAG vs. PXG | =0.8056 (17/18) | ns | |
| from Figure 2 (in nmoles carbonyls mg-1 protein per 5-year interval) | CAT vs. PEX | <0.0001 (33/31) | **** | ||
| CAT vs. POAG | <0.0001 (33/19) | **** | |||
| LECs/ | CAT | 1.506 ± 0.116 | CAT vs. PXG | <0.0001 (33/17) | **** |
| capsule | PEX | 4.524 ± 0.137 | PEX vs. POAG | =0.1425 (31/19) | ns |
| POAG | 5.048 ± 0.139 | PEX vs. PXG | <0.0001 (31/17) | **** | |
| PXG | 8.364 ± 0.322 | POAG vs. PXG | <0.0001 (19/17) | **** | |
| B. Protein concentration versus disease (non-age dependent) | |||||
| Mean concentration (± SE) | |||||
| from values for horizontal straight lines in Figure 3 (in mg protein ml-1) | CAT vs. PEX | =0.1225 (20/19) | ns | ||
| CAT vs. POAG | <0.0001 (20/17) | **** | |||
| AH | CAT | 0.16 ± 0.0074 | CAT vs. PXG | <0.0001 (20/18) | **** |
| PEX | 0.23 ± 0.0093 | PEX vs. POAG | =0.0003 (19/17) | *** | |
| POAG | 0.34 ± 0.0136 | PEX vs. PXG | <0.0001 (19/18) | **** | |
| PXG | 0.42 ± 0.0162 | POAG vs. PXG | =0.0303 (17/18) | * | |