Table 1 of
Sharma, Mol Vis 2018; 24:801-817. Table 1 of
Sharma, Mol Vis 2018; 24:801-817.
Table 1. Top hub nodes with more than 20 known interactions with other genes in the constructed network of PEX syndrome associated genes.
| Gene symbol | Gene name | Number of interactions |
|---|---|---|
| FN1 | fibronectin 1 | 755 |
| CLU | clusterin | 90 |
| APOA1 | apolipoprotein A-I | 88 |
| SEBOX | SEBOX homeobox | 83 |
| TGM2 | transglutaminase 2 | 82 |
| APOE | apolipoprotein E | 67 |
| TGFB1 | transforming growth factor, beta 1 | 58 |
| PRDX2 | peroxiredoxin 2 | 57 |
| A2M | alpha-2-macroglobulin | 42 |
| C3 | complement component 3 | 35 |
| FGB | fibrinogen beta chain | 33 |
| VCAN | versican | 33 |
| SDC2 | syndecan 2 | 32 |
| FGA | fibrinogen alpha chain | 31 |
| FGF2 | fibroblast growth factor 2 (basic) | 30 |
| MMP2 | matrix metallopeptidase 2 | 29 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 28 |
| LAMB1 | laminin, beta 1 | 27 |
| C1QA | complement component 1, q subcomponent, A chain | 24 |
| CRYAA | crystallin, alpha A | 24 |
| APCS | amyloid P component, serum | 22 |
| FGG | fibrinogen gamma chain | 22 |
| ELN | elastin | 21 |