Figure 1. Experimental overview. Branch retinal vein occlusion (BRVO) was induced in both eyes of six Danish Landrace pigs. After successful occlusion had been observed, the right eyes were given an intervention with bevacizumab while the left eyes received an injection containing saline water (NaCl). Fluorescein angiography was conducted 5 days after BRVO to confirm that the veins remained occluded. The eyes were enucleated and dissected 15 days after BRVO. Paired retinal samples from five animals were used for proteomic analysis with mass spectrometry followed by western blotting. Thus, samples with BRVO + bevacizumab (n=5) were compared to BRVO + NaCl (n=5). Eyes from one animal were used for validation with immunohistochemistry.