Table 4 of Davoudi, Mol Vis 2018; 24:59-74.

Table 4. Association results for sarcoidosis-associated anterior uveitis.

 
Gene  
Chr  
SNP  
Ref/ Alternate Allele Anterior Uveitis versus Controls Anterior Uveitis versus Other (Intermediate, Posterior and Pan) Uveitis
Ref Allele Freq, Cases (n=24) Ref Allele Freq, Controls (n=32) OR 95% CI Pcorr Ref Allele Freq, Ant Uveitis Cases (n=24) Ref Allele Freq, Other Uveitis (n=21) OR 95% (CI) Pcorr
CFH Y402H 1 rs1061170 C/T 0.33 0.38 0.83 0.38–1.83 1.00 0.33 0.36 0.90 0.38–2.15 0.86
IL23R 1 rs11209026 A/G 0.09 0.05 2.03 0.43–9.57 0.29 0.09 0.05 2.00 0.35–11.54 0.36
IL23R 1 rs11465804 G/T 0.08 0.06 1.36 0.32–5.75 0.73 0.08 0.05 1.82 0.32–10.47 0.43
IL23R 1 rs7517847 G/T 0.39 0.30 1.52 0.48–4.78 0.50 0.39 N/A N/A N/A 1.00
TGF-β2 1 rs1891467 G/A 0.39 0.23 2.06 0.89–4.76 0.09 0.39 0.24 2.02 0.79–5.13 0.16
CCR 5 3 rs1799987 A/G* 0.52 0.45 1.31 0.62–2.78 0.50 0.48 0.50 0.92 0.40–2.11 1.00
BTNL2 6 rs9268480 T/C 0.34 0.22 1.85 0.78–4.37 0.14 0.34 0.29 1.29 0.52–3.23 0.63
BTNL2 6 rs9268482 T/A 0.34 0.22 1.85 0.78–4.37 0.14 0.34 0.29 1.29 0.52–3.23 0.86
HLA- DQA1 6 rs17843604 C/T* 0.46 0.52 0.79 0.38–1.68 0.45 0.54 0.43 1.58 0.68–3.63 0.20
HLA- DRA 6 rs7192 T/G 0.23 0.47 0.33 0.14–0.79 0.007 0.23 0.48 0.32 0.13–0.82 0.02
HLA- DRA 6 rs7194 G/A 0.23 0.47 0.33 0.14–0.79 0.006 0.23 0.48 0.32 0.13–0.82 0.02
HLA- DRB1 6 rs615672 C/G 0.35 0.48 0.58 0.27–1.26 0.34 0.35 0.45 0.66 0.28–1.55 0.48
HLA- DRB5 6 rs17203612 T/A 0.50 0.25 3.00 1.32–6.80 0.014 0.50 0.31 2.23 0.92–5.39 0.10
HSP-70/Hom 6 rs2075800 T/C 0.35 0.36 0.98 0.45–2.14 1.00 0.35 0.24 1.76 0.70–4.42 0.15
HSP-70/Hom 6 rs1043620 T/C 0.02 0.08 0.27 0.03–2.35 0.26 0.02 0.03 0.72 0.04–11.97 0.55
LTA 6 rs909253 G/A 0.42 0.36 1.27 0.59–2.75 0.64 0.42 0.60 0.49 0.21–1.13 0.12
NOTCH4 6 rs715299 G/T 0.45 0.31 1.83 0.83–4.06 0.20 0.45 0.31 1.86 0.77–4.50 0.26
RAB23 6 rs1040461 T/C 0.11 0.00 N/A N/A 0.001 0.11 0.02 5.26 0.59–47.03 0.10
TNF-α 6 rs1800629 A/G 0.05 0.17 0.23 0.05–1.09 0.03 0.05 0.29 0.12 0.02–0.57 0.001
TLR4 9 rs4986790 G/A 0.02 0.08 0.25 0.03–2.22 0.20 0.02 0.02 0.87 0.05–14.39 1.00
ANXA11 10 rs2789679 T/A 0.33 0.41 0.73 0.33–1.60 0.34 0.33 0.29 1.25 0.51–3.07 0.86
ANXA11 10 rs2573346 A/G 0.36 0.41 0.84 0.38–1.84 0.55 0.36 0.29 1.43 0.58–3.54 0.86
ANXA11 10 rs1049550 A/G 0.39 0.41 0.92 0.42–2.02 0.64 0.39 0.29 1.57 0.64–3.89 0.73
ANXA11 10 rs61860052 A/C 0.19 0.03 7.15 1.47–34.86 0.004 0.19 0.07 3.00 0.75–11.92 0.09
ANXA11 and PLAC9 10 rs1953600 T/C 0.36 0.41 0.84 0.38–1.84 0.55 0.36 0.29 1.43 0.58–3.54 0.86
C10ORF67/10p12.2 10 rs1398024 T/G 0.23 0.20 1.17 0.47–2.89 0.86 0.23 0.19 1.26 0.45–3.51 1.00
IL2RA 10 rs12722489 T/C 0.16 0.08 2.23 0.66–7.55 0.18 0.16 0.10 1.80 0.49–6.66 0.31
CDCC88B 11 rs671976 A/G 0.41 0.50 0.69 0.32–1.50 0.32 0.59 0.40 2.12 0.90–5.02 0.11
CDCC88B 11 rs479777 C/T 0.23 0.28 0.75 0.31–1.83 0.63 0.23 0.29 0.74 0.28–1.94 0.69
OS9 12 rs11172300 T/C 0.34 0.36 0.92 0.41–2.06 0.69 0.34 0.38 0.84 0.35–2.03 0.64
OS9 12 rs701007 A/C 0.38 0.42 0.82 0.38–1.77 0.44 0.38 0.43 0.80 0.34–1.86 0.48
OS9 12 rs799265 G/A 0.40 0.42 0.90 0.42–1.92 0.78 0.40 0.48 0.72 0.31–1.67 0.38
TGF-β3 14 rs3917200 G/A 0.23 0.09 2.84 0.95–8.52 0.07 0.23 0.12 2.18 0.68–7.01 0.20
TGF-β3 14 rs3917165 T/C 0.18 0.08 2.62 0.80–8.64 0.07 0.18 0.05 4.44 0.89–22.31 0.03
HERC2 15 rs916977 T/C 0.32 0.30 1.11 0.48–2.54 1.00 0.32 0.33 0.93 0.38–2.30 0.86

*Effect and reference allele are reversed for anterior uveitis versus other uveitis

Davoudi, Mol Vis 2018; 24:59-74. http://www.molvis.org/molvis/v24/59

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